Bicarbonate Inhibits N-Nitrosation in Oxygenated Nitric Oxide Solutions

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Efficient nitrosation of glutathione by nitric oxide☆

Nitrosothiols are increasingly regarded as important participants in a range of physiological processes, yet little is known about their biological generation. Nitrosothiols can be formed from the corresponding thiols by nitric oxide in a reaction that requires the presence of oxygen and is mediated by reactive intermediates (NO₂ or N₂O₃) formed in the course of NO autoxidation. Because the aut...

متن کامل

Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases.

The Ras superfamily of small GTPases cycle between inactive GDP-bound and active GTP-bound states to modulate a diverse array of processes involved in cellular growth control. While the basic mechanisms by which GTPase regulatory proteins regulate GTPase substrates have been revealed through numerous studies, detailed studies into the mechanism(s) of free radical-mediated GTPase regulation have...

متن کامل

Nitric oxide produced by THAL nitric oxide synthase inhibits TGF.

Nitric oxide (NO) produced by neuronal NO synthase (nNOS) in the macula densa decreases tubuloglomerular feedback (TGF). NO produced by NOS in the thick ascending limb (THAL) inhibits NaCl transport. We hypothesized that NO produced by NOS in the THAL reaches the macula densa and inhibits TGF. Rabbit afferent arterioles and attached macula densa were simultaneously microperfused in vitro. TGF r...

متن کامل

Absorption Spectra of Nitric Oxide in Solutions

The absorption spectra of nitric oxide in aromatic and aliphatic hydrocarbons, in alcohols and in water were investigated. The experimental results show that the broad structureless absorption bands observed rise from charge transfer between the solvent and NO. Thermochemical data indicate that the solvent-NO interactions are due to contacts in solution without the formation of a stable complex...

متن کامل

An N-nitrosation reactivity-based two-photon fluorescent probe for the specific in situ detection of nitric oxide.

In situ fluorescence imaging of nitric oxide (NO) is a powerful tool for studying the critical roles of NO in biological events. However, the selective imaging of NO is still a challenge because most currently available fluorescent probes rely on the o-phenylenediamine (OPD) recognition site, which reacts with both NO and some abundant reactive carbonyl species (RCS) (such as dehydroascorbic ac...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1996

ISSN: 0021-9258

DOI: 10.1074/jbc.271.42.25859